Clinical Studies 2017-04-04T20:54:41+00:00

Clinical Studies

A Cetylated Fatty Acid Topical Cream with Menthol Reduces Pain and Improves Functional Performance in Patients with Arthritis
Published in the Journal of Strength & Conditioning, May 2005

Effects of Treatment with a Cetylated Fatty Acid Topical Cream on Static Postural Stability and Plantar Pressure Distribution in Patients with Knee Osteoarthritis
Published in the Journal of Strength & Conditioning, February 2005

The Effects of a Cetylated Fatty Acid Topical Cream on Functional Mobility and Quality of Life of Patients with Osteoarthritis
Published in the Journal of Rheumatology, August 5, 2004

Distribution of Cetylated Fatty Acids in Rats after Oral or Topical Administration
October 31, 2002

Digestion and Metabolism of Cetylated Fatty Acids in Rats
October 1, 2002

A Preliminary Study for the Use of Celadrin™ for the Treatment of Psoriasis
September 17, 2002

Cetylated Fatty Acids Improve Knee Function in Patients with Osteoarthritis
Published in the Journal of Rheumatology, February 14, 2002

Evaluation of a Topical Cream Containing Cetylated Fatty Acids
August 29, 2001

The Effect of a Cetylated Fatty Acid (CFA) for Improving Quality of Life in Canines
2001

A Fatty Acid Ester (CMC) Improves Quality of Life Outcomes in Osteoarthritis (OA) Patients
2001

Celadrin® Improves Walking Performance-Oral Cetylated Fatty Acids for the Improvement of Functional Ability and Pain in Patients with Knee Osteoarthritis
Jay K Udani 2,3, BetsySingh 4,Michelle Torreliza2, Matt Crabtree2, Grant Zhang4, 2011

The Effects of Cetylated Fatty Acid Cream on Pain, Range of Motion and Quality of Life of Patients with Osteoarthritis
Kraemer WJ, Ratamess NA, Anderson JA, Tiberio DP, Joyce ME, Messinger BN, French DN, Sharman MJ, Rubin MR, Gomez AL, Volek JS, Hesslink R Jr, 2003

The Effects of a Cetylated Fatty Acid Cream on Functional Mobility and Performance in Patients with Osteoarthritis
Ratamess NA, Kraemer WJ, Anderson JA, Tiberio DP, Joyce ME, Messinger BN, French DN, Sharman MJ, Rubin MR, Gomez AL, Volek JS, Hesslink R Jr., 2003

Absorption and Metabolism of a Cetylated Fatty Acid
Islam A, Gallaher C.M., and Gallaher D.D., 2003

Digestion and Metabolism of Cetylated Fatty Acids in Rats
Gallaher D.D., Gallaher C.M., Hesslink R. Jr., 2002

The Effects of a Cetylated Fatty Acid Complex on Canine Osteoarthritis
Hesslink R.L., and Sprouse S, 2002

A Fatty Acid Ester (CMC) Improves Quality of Life Outcomes in Osteoarthritis (OA) Patients
Barathur R.R., Bookout J.B., Sreevatsan S, Freedland E.S. and Hesslink Jr., R.L., 2001

Bacterial Reverse Mutation Ames Test Screening
MDS Pharma, Les Oncins, France, 2002

Evaluation of Topical Cetylated Fatty Acid Application to Psoriasis Patients
Dermatologist Medical Group of North County, Inc., 2002

The Acute Toxicology of Oral Cetylated Fatty Acid Gavage CD-1 Mouse Model
Perry Scientific, Inc., 2001

Evaluation of a Topical Cream Containing Cetylated Fatty Acids Using Hairless Mouse Model
Perry Scientific, Inc., Study No. 00-1076, 2000

Q – What is Celadrin®?

A – Celadrin® is one of the newest, most effective natural anti-inflammatory compounds that safely promotes flexibility and healthy joint function. Clinical studies have reported significant results without any side effects.

Q – What is Celadrin® made from?

A – Celadrin® is made from a patented complex blend of special esterified fatty acids, derived from bovine tallow oil.

Q – How does Celadrin® work?

A – Celadrin® decreases inflammation and lubricates cell membranes throughout the body, restoring fluids that cushion bones and joints to promote flexibility and mobility. Over time, because of the reduction of inflammation delivered by using Celadrin®, the joints and surrounding tissue have an opportunity to promote healthy joints.

Celadrin® works similar to, but much more dramatically than the essential fatty acids EPA and DHA from fish oils. Celadrin®’s complex blend of esterified fatty acids; provide many vital and beneficial effects for the inflammatory responses in the body. Celadrin® induces changes at the cellular level, in the cell membranes which positively affect the responsiveness of the cell membranes. This aids in the reduction of cartilage breakdown in the joints.

Q – Is their any science behind Celadrin®?

A – Celadrin® has been clinically studied at various times with results published in the prestigious Journal of Rheumatology for both oral and topical applications as well as the Journal of Strength and Conditioning Research.

For oral application, Celadrin® was studied using a double-blind, multi-center, placebo-controlled trial (the most scientifically validated type). Sixty-four participants between the ages of 37 to 77 were given Celadrin® capsules and were evaluated at the beginning of the trial, at 30 days and at the end of the 68 day study. Compared to those given a placebo, those who were given Celadrin® had more flexibility, fewer aches, less pain and were able to walk further distances than the placebo group. The study therefore concluded that Celadrin®, when taken orally improved joint and mobility problems.

For topical application of Celadrin® cream, a study was conducted at the University of Connecticut, involving 42 patients with osteoarthritis of the knee. Participants used either Celadrin® or a placebo cream. Patients were evaluated before application of the cream, 30 minutes after, and then again following a 30 day treatment period during which the cream was applied twice a day, morning and evening. The researchers evaluated physical function, postural movement, pain and range of motion. The test included how long it took the patient to get up and go from a chair, stair climbing, endurance, and mobility of the knee. The group receiving Celadrin® had outstanding results with reduced pain and stiffness, improved balance and strength and better mobility. 100% of the patients in the study showed significant benefit compared to the patients on the placebo. Even more exiting was that patients experienced a dramatic improvement in all aspects tested after only 30 minutes of applying the cream with cumulative benefits occurring after 30 days.

An additional study, as an extension of this original study, confirmed earlier research showing improvement in elbow, wrist and knee mobility and significant reduction in pain.

Q – Which is better, Celadrin® cream or Celadrin® pills?

A – Both oral and topical applications were shown to be equally effective in a separate study, where it was proven that the Esterified Fatty Acids (EFAC) found in Celadrin®, could be absorbed by either method (95.1% absorption rate proven through a University of Minnesota labeled study) into the body.

Q – How does Celadrin® compare to other natural joint health products?

A – Celadrin®’s beneficial effects have been proven superior in results to Glucosamine, Chondroitin, MSM, SAMe and other natural joint health products.

Celadrin® provides restoration of a wide range of joint health conditions including sports injuries to joints, muscles, tendons and deep tissue.

Q – Can Celadrin® work well in conjunction to taking Glucosamine?

A – The cause of wear on the joint area can be attributable to inflammation as well as insufficient lubrication and cell membrane fluidity. Glucosamine assists in the rebuilding of cartilage & the overall structure of the joint and has shown moderate effects on people with osteoarthritis. Celadrin® provides continuous lubrication and allows the cell membrane to repel inflammatory chemicals. Celadrin® stops the cascade of inflammation and the assaults on the membrane which cause it to stiffen. Celadrin® empowers glucosamine to perform faster and more efficiently in building joint cartilage as well as accelerating and promoting joint health. The dual action of Celadrin® and glucosamine provide rapid joint cushioning, quickly alleviate inflammation, build cartilage and restore the entire joint area.

Q – Does Celadrin® replace fish oils?

A – Although Celadrin® is a fatty acid it does not replace the need for Omega 3 fatty acids from fish oils or flaxseed oil. They are complementary and can be taken together; each having their own beneficial action.

Q – Can I take Celadrin® with Coumadin (Warfarin)?

A – The most common question received by the Celadrin® website is about the use of Coumadin or Warfarin and Celadrin®. Celadrin® is a combination of fatty acids. Patients should take Coumadin as directed by their healthcare provider and follow any directions from their provider about interactions with other drugs or supplements.

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